GENE-62. IDENTIFICATION OF FGFR4 p.G388R VARIANT IN CEREBELLAR HEMANGIOBLASTOMAS
نویسندگان
چکیده
منابع مشابه
Surgical treatment of cerebellar hemangioblastomas
BACKGROUND Hemangioblastomas (HBL) are uncommon tumors of the central nervous system (CNS), corresponding to 1-2.5% of all intracranial tumors. They can present sporadically or in patients with von Hippel-Lindau (VHL) disease and are most often located in the cerebellum, brainstem, and spinal cord. VHL disease is a multiple neoplasia syndrome inherited in an autosomal dominant fashion and cause...
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OBJECT Hemangioblastomas of the central nervous system are highly vascularized benign tumors. When the tumors are located in the medulla oblongata, intraoperative bleeding can make the surgical procedure very difficult. Preoperative embolism has been performed in cases of hemangioblastoma in recent decades. However, the complications of the embolization can result in fatal consequences, especia...
متن کاملThe natural history of cerebellar hemangioblastomas in von Hippel-Lindau disease.
BACKGROUND AND PURPOSE Cerebellar hemangioblastomas (HBs) are traditionally classified into different morphologic types: cystic and solid. We have observed the progression from solid to cystic and have reviewed the cases seen at the regional von Hippel-Lindau (VHL) clinic to document the frequency of this progression. METHODS A retrospective review of the notes and images of all patients with...
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Progressive Supranuclear Palsy (PSP) is an atypical Parkinsonism noted for postural instability, early falls, and a supranuclear vertical gaze palsy. However, since its original description, several variants were described. One of the rarer variants is PSP-C, further adding to the diverse clinical. As a result, misdiagnosis of PSP-C as multiple system atrophy, or a spinocerebellar degeneration ...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2019
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/noz175.464